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Intra Cytoplasmic Sperm Injection (ICSI) Treatment: Procedure, Benefits, Cost

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Intra Cytoplasmic Sperm Injection (ICSI) Treatment: Procedure, Benefits, Cost

What Is ICSI?

In case of male fertility issues, an intracytoplasmic sperm injection (ICSI) is the most helpful. It involves injecting live sperm into a person’s eggs in a laboratory which helps create an embryo. A form of in-vitro fertilization (IVF) procedure, ICSI promotes fertilization through the direct injection of a single sperm into a single egg. Like IVF, in ICSI as well, the doctor implants the fertilized egg into the uterus. Pregnancy occurs if the embryo attaches to the lining of your uterus.

What Is the Success Rate Of ICSI?

The success rate of ICSI is like that of IVF. Approximately, 6 out of 10 IVF procedures are aided by ICSI. It’s estimated that 50% to 80% of ICSI attempts result in fertilization

Why Would I Need ICSI?

ICSI is recommended by doctors in cases of male infertility. You may need an ICSI in the following cases:
  • A condition called Anejaculation which is the inability to ejaculate
  • Blockage in their male reproductive system
  • Low sperm count
  • Poor sperm quality
  • Retrograde ejaculation, a condition where the semen flows backward into the bladder
  • If traditional IVF hasn’t led to the creation of embryos
  • If the egg donor is above the age of 35
  • If cryopreservation is being used for conception

How Can I Prepare For ICSI?

Before the ICSI procedure, the doctor collects the egg and the sperm using the following processes:
  • Ovulation induction: The person supplying the eggs receives medication injections for eight to 14 days to stimulate the ovaries to produce eggs. 
  • Egg retrieval: The doctor will use transvaginal ultrasound to insert a thin needle through the wall of the vagina into the ovaries. A suction device connected to the needle draws out and collects the eggs.
  • Sperm collection also takes place on the same day as egg retrieval. A semen analysis takes place immediately to check sperm volume, mobility, and quality.

What Happens During An ICSI?

During ICSI, your doctor will follow these steps:
  • Use a pipette (small glass tube with a suction bulb) to hold the mature egg in place on a lab dish
  • Immobilize and pick up one sperm using a thin needle
  • Insert the needle into the egg to reach the cytoplasm
  • Inject the sperm into the cytoplasm
  • Withdraw the needle from the egg
  • After this, the doctor will monitor the fertilized egg in the laboratory for signs of successful fertilization. Within five to six days, a healthy fertilized egg should divide into cells, forming a blastocyst.
  • An embryo transfer occurs on either the fifth or sixth day following the egg retrieval procedure or commonly the transfer is delayed for a month or even years.
  • Again, using a transvaginal ultrasound, the doctor will insert a catheter into your vagina and inject the embryo into your uterus. For pregnancy to happen, the embryo needs to attach to your uterus. You will be told to wait at least two weeks before taking a pregnancy test.

To Conclude

Compared to traditional IVF, ICIS appears to be more successful in helping those experiencing male infertility become parents. Some centers do ICSI for all people, regardless of infertility diagnosis.

Cost Of ICSI

The cost of ICSI varies from one clinic to another but on an average, the cost of ICSI in India is between INR 240,000 to 250,000 per cycle. For more information about the procedure and the cost, you can contact Motherhood Fertility & IVF Centre by calling 08067238900 or book an appointment with us.


An ICSI is recommended in cases of male infertility when the man is unable to ejaculate, has blockage in the reproductive system, low sperm count, etc.
A few complications can occur with ICSI which are as follows:
  • There can be damage to some or all the eggs during needle penetration
  • An egg may not fertilize after the sperm injection
  • An embryo may stop developing in the lab or after embryo transfer
ICSI benefits those with male infertility to a greater degree than traditional IVF.

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