Author: Dr. Sharvari Mundhe

Qualification: MBBS, MS, DNB, FRM, DRM


Embryo transfer is a pivotal moment in the IVF (In Vitro Fertilization) process. After the transfer, there’s a period of anticipation as patients wait to see if the procedure is successful. This period, often referred to as the “2-week wait,” can be filled with anxiety and hope. During this time, many individuals keenly observe their bodies for any signs that might indicate a successful embryo transfer and positive pregnancy signs.

1.Breast Tenderness
One of the earliest signs of pregnancy can be breast tenderness. This is due to the surge in hormones, especially estrogen and progesterone, which cause the breasts to become more sensitive. The breasts might feel swollen, sore, or even tingly. The area around the nipples, known as the areola, may darken.

Why it Happens: The body starts preparing for breastfeeding soon after conception. The increased blood flow and hormonal changes cause the breast tissues to expand, leading to tenderness.

A small amount of light spotting or bleeding can be one of the first signs of positive pregnancy. This is known as implantation bleeding and occurs when the fertilized embryo attaches itself to the lining of the uterus.

Why it Happens: As the embryo burrows into the uterine wall, it might displace some of the lining, leading to light bleeding. This typically happens about 6-12 days after ovulation.

Bloating in the early stages of pregnancy can make you feel uncomfortable. It’s similar to the sensation you might experience at the beginning of your menstrual cycle.

Why it Happens: The progesterone hormone, which increases after conception, slows down the digestive process, leading to gas, bloating, and constipation.

Mild uterine cramping without bleeding can be an early positive pregnancy sign. These cramps might feel like light pulling or twinges in the lower abdomen.

Why it Happens: As the embryo implants itself into the uterine wall, the uterus might contract, leading to cramping sensations.

Often termed as ‘morning sickness,’ nausea can strike at any time of the day. Some women might also experience vomiting.

Why it Happens: The exact cause is unknown, but it’s believed that the rapid increase in the hormone hCG after conception plays a role. The heightened sense of smell and excess saliva production can also contribute to feelings of queasiness.

6.Increased Cervical Mucus
After conception, there might be an increase in vaginal discharge, which is usually clear, stretchy, and odorless – similar to the consistency of egg whites.

Why it Happens: This discharge, known as leukorrhea, is caused by an increase in hormone levels and blood flow to the pelvis. It helps keep the cervix healthy and moist during pregnancy.

Feeling unusually tired without any reason can be a clear sign of pregnancy. This fatigue can be overwhelming and might make you feel exhausted by the simplest of tasks.

Why it Happens: The rise in the hormone progesterone can make you feel sleepy. Additionally, the body works overtime to support the growing fetus, leading to increased tiredness.

8.Changes in Basal Body Temperature
There’s a sustained elevated basal body temperature during the early pregnancy phase.

Why it Happens: After ovulation, the body’s basal temperature increases to create a conducive environment for the fertilized egg. If the temperature remains elevated for more than two weeks, it could indicate pregnancy.

9.Frequent Urination
You might find yourself visiting the bathroom more often, even before you miss a period.

Why it Happens: The increase in blood volume makes the kidneys process more fluid, which ends up in the bladder. This symptom might intensify as the pregnancy progresses and the growing fetus exerts pressure on the bladder.

10.Mood Swings
Emotional roller-coaster rides can be a common occurrence, with feelings ranging from joy and excitement to anxiety and irritability.

Why it Happens: The surge in hormones, especially estrogen and progesterone, can affect mood-regulating neurotransmitters in the brain.

The journey of IVF and embryo transfer is filled with hope, anticipation, and anxiety. While observing positive pregnancy signs can be encouraging, it’s essential to remain patient and wait for a confirmed pregnancy test. Regardless of the outcome, the journey is a testament to the strength and resilience of those hoping to expand their families.


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